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Developmental Therapeutics Program (DTP)
Last Updated: 08/18/15

NCI Yeast Anticancer Drug Screen

The NCI Yeast Anticancer Drug Screen has screened tens of thousands of compounds the ability to inhibit the growth of selected yeast strains altered in DNA damage repair or cell cycle control. Compounds are initially screened against a panel of 6 yeast strains at a single concentration (Stage0). Compounds with activity in Stage0 are rescreened against the same panel at 2 concentrations (Stage1). Selected compounds with activity in Stage1 that also show selectivity are rescreened against a panel of 13 yeast strains at 5 concentrations (Stage2). Available here are screening results for compounds that are not covered by a confidentiality agreement. These pages will be updated periodically. Last update was September 2001.

Experimental Design

Browse Stage0 / Stage1 Results By Activity Pattern

Stage2 Data

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Release Notes / Download Datasets

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