| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX009 (ip) | median survival time | saline | 0.23 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 0.39 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 0.65 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 1.08 mg/kg/injection | 149.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 1.8 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 3.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 0.75 mg/kg/injection | 99.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 0.93 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 0.93 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 0.93 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 0.93 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 1.5 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 1.56 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 1.56 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 75; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 1.56 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 1.56 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 1.56 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 2.59 mg/kg/injection | 136.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 2.59 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 2.59 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 2.59 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 2.59 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 75; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 3.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 4.3 mg/kg/injection | 192.0 | Antitumor endpoint evaluated on day 75; 06/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 4.32 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 4.32 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 4.32 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 4.32 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 6.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 7.2 mg/kg/injection | 136.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 7.2 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 7.2 mg/kg/injection | 193.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 7.2 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 75; 06/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 7.2 mg/kg/injection | 170.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 12.0 mg/kg/injection | 91.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 12.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 12.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 75; 00/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 12.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 02/08 animals surviving on day 9 |
| Q04DX003 (ip) | median survival time | saline | 12.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 05/08 animals surviving on day 13 |
| Q04DX003 (ip) | median survival time | saline | 12.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 06/08 animals surviving on day 5 |