| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 59.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 99.0 | Antitumor endpoint evaluated on day 11; 02/02 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 261.0 | Antitumor endpoint evaluated on day 11; 02/02 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 73.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 7.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 53.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 59.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 99.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 93.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 209.0 | Antitumor endpoint evaluated on day 11; 02/02 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 81.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 58.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 72.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 46.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 7.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 52.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 35.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -5.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 17.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -29.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -43.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -19.0 | Antitumor endpoint evaluated on day 11; 02/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/03 animals surviving on day 11 |
| Q04DX004 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 8.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | -10.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -61.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 00/05 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 156.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 75.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | 2.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 00/06 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline with Tween-80 | 1.0 mg/kg/injection | 75.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline with Tween-80 | 2.0 mg/kg/injection | 27.0 | Antitumor endpoint evaluated on day 15; 05/05 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline with Tween-80 | 4.0 mg/kg/injection | 80.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (sc) | mean tumor weight change | saline with Tween-80 | 8.0 mg/kg/injection | 4.0 | Antitumor endpoint evaluated on day 15; 05/06 animals surviving on day 15 |