| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 80.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 18.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -4.0 | Antitumor endpoint evaluated on day 11; 02/03 animals surviving on day 11 |
| Q04DX004 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 68.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 58.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 40.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 9.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 45.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 40.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 10.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 11.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 10.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | 8.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -3.0 | Antitumor endpoint evaluated on day 15; 04/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | 49.0 | Antitumor endpoint evaluated on day 15; 04/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -54.0 | Antitumor endpoint evaluated on day 15; 05/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -70.0 | Antitumor endpoint evaluated on day 15; 06/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 00/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 00/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 00/06 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 00/01 animals surviving on day 15 |
| Q04DX004 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 15; 01/06 animals surviving on day 15 |