| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q04DX003 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 13.0 | Antitumor endpoint evaluated on day 14; 06/06 animals surviving on day 14 |
| Q04DX003 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 33.0 | Antitumor endpoint evaluated on day 14; 05/06 animals surviving on day 14 |
| Q04DX003 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | 4.0 | Antitumor endpoint evaluated on day 14; 04/06 animals surviving on day 14 |
| Q04DX003 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 14; 01/06 animals surviving on day 14 |