| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q04DX002 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 2.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 43.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 33.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | -45.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 12.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 4.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -79.0 | Antitumor endpoint evaluated on day 9; 05/05 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | 1.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | 9.0 | Antitumor endpoint evaluated on day 9; 05/05 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | -54.0 | Antitumor endpoint evaluated on day 9; 05/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 9; 01/06 animals surviving on day 9 |
| Q04DX002 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 19.0 | Antitumor endpoint evaluated on day 9; 06/06 animals surviving on day 9 |