| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX001 (ip) | mean survival time | saline with Tween-80 | 5.3 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline with Tween-80 | 12.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline with Tween-80 | 15.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.5 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 5.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 10.0 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on day 5 |
| Q04DX003 (ip) | median survival time | saline | 20.0 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on day 5 |