| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q03HX008 (ip) | median survival time | saline | 0.5 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (ip) | median survival time | saline | 1.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (ip) | median survival time | saline | 2.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (ip) | median survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 06/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (ip) | mean survival time | other | 0.25 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (ip) | mean survival time | other | 0.5 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (ip) | mean survival time | other | 1.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (ip) | mean survival time | other | 2.0 mg/kg/injection | 379.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (oral) | median survival time | saline | 1.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (oral) | median survival time | saline | 2.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (oral) | median survival time | saline | 4.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX008 (oral) | median survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (ip) | median survival time | saline | 0.12 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (ip) | median survival time | saline | 0.25 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (ip) | median survival time | saline | 0.5 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (ip) | median survival time | saline | 1.0 mg/kg/injection | 211.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (oral) | median survival time | saline | 0.25 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (oral) | median survival time | saline | 0.5 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (oral) | median survival time | saline | 1.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q03HX024 (oral) | median survival time | saline | 2.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 21; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 40; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 62; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 2.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 45; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 3.0 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 3.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 3.0 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 3.0 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 64; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 3.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 3.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 46; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 3.0 mg/kg/injection | 123.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 45; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 40; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 62; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 21; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 4.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 138.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 59; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 46; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 69; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 136.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 5.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 6.0 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 6.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 64; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 6.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 6.0 mg/kg/injection | 148.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 159.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 45; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 62; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 40; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 21; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.0 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 172.0 | Antitumor endpoint evaluated on day 59; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 46; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 69; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 151.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 158.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 175.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 8.4 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 10.0 mg/kg/injection | 185.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 10.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 12.0 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 12.0 mg/kg/injection | 87.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on day 5 |
| Q01DX001 (ip) | median survival time | saline | 12.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 64; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 172.0 | Antitumor endpoint evaluated on day 59; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 163.0 | Antitumor endpoint evaluated on day 46; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 172.0 | Antitumor endpoint evaluated on day 69; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 175.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 14.0 mg/kg/injection | 164.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 61.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 21; 04/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 88.0 | Antitumor endpoint evaluated on day 40; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 62; 04/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 45; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 16.0 mg/kg/injection | 85.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 23.0 mg/kg/injection | 89.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 23.0 mg/kg/injection | 88.0 | Antitumor endpoint evaluated on day 69; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 23.0 mg/kg/injection | 60.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 21; 00/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 6.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 9.0 mg/kg/injection | 184.0 | Antitumor endpoint evaluated on day 5; 06/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 9.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 5; 09/09 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 12.0 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 12.0 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 5; 08/09 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 15.0 mg/kg/injection | 80.0 | Antitumor endpoint evaluated on day 5; 04/07 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 15.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 18.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 5; 00/05 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 18.0 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 5; 08/09 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 21.0 mg/kg/injection | 74.0 | Antitumor endpoint evaluated on day 5; 08/09 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 21.0 mg/kg/injection | 70.0 | Antitumor endpoint evaluated on day 5; 04/07 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 3.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 3.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 5.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 5.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 5.0 mg/kg/injection | 142.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 5.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 55; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 8.4 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 8.4 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 8.4 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 8.4 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 55; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 14.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 14.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 14.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 14.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 55; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 23.0 mg/kg/injection | 51.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | water | 23.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 55; 01/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | none | 2.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | none | 4.0 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | none | 8.0 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | none | 16.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | none | 32.0 mg/kg/injection | 60.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 136.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 159.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 149.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 139.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 121.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 3.0 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 3.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 3.0 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 64; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 153.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 171.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 138.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 142.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 219.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 138.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 148.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 158.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 153.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 335.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 124.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 149.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 69; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 6.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 6.0 mg/kg/injection | 159.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 6.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 6.0 mg/kg/injection | 179.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 6.0 mg/kg/injection | 179.0 | Antitumor endpoint evaluated on day 30; 05/05 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 6.0 mg/kg/injection | 242.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 6.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 64; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 149.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 209.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 307.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 176.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 167.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 186.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 191.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 163.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 179.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 149.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 159.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 151.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 179.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 190.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 8.4 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 69; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 8.4 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 9.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 183.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 198.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 136.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 176.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 12.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 12.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | saline | 12.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 64; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 14.0 mg/kg/injection | 153.0 | Antitumor endpoint evaluated on day 69; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 14.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 148.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 175.0 | Antitumor endpoint evaluated on day 60; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 05/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 88.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 23.0 mg/kg/injection | 88.0 | Antitumor endpoint evaluated on day 69; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 23.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 03/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 00/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 40.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 00/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 64.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 00/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | water | 4.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | water | 5.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | water | 5.0 mg/kg/injection | 148.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | water | 6.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | water | 8.0 mg/kg/injection | 89.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | water | 10.0 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | water | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/06 animals surviving on day 5 |
| Q01DX001 (ip) | mean survival time | water | 10.0 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | water | 20.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | water | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | other | 2.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | other | 4.0 mg/kg/injection | 156.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | other | 8.0 mg/kg/injection | 378.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | other | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (oral) | median survival time | saline | 4.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (oral) | median survival time | saline | 8.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (oral) | median survival time | saline | 16.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (oral) | median survival time | saline | 32.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | median survival time | saline | 0.5 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | median survival time | saline | 1.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | median survival time | saline | 2.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | median survival time | saline | 4.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 2.7 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 2.7 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 2.7 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 2.7 mg/kg/injection | 156.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 2.7 mg/kg/injection | 148.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 3.5 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 3.5 mg/kg/injection | 167.0 | Antitumor endpoint evaluated on day 5; 09/09 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 145.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 167.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 204.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 188.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 5.3 mg/kg/injection | 187.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 5.3 mg/kg/injection | 193.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 191.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 123.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 86.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 45; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 12.0 mg/kg/injection | 81.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 12.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 18.0 mg/kg/injection | 70.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 18.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | other | 0.25 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | other | 0.5 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | other | 1.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | other | 2.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (sc) | mean survival time | other | 0.25 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (sc) | mean survival time | other | 0.5 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (sc) | mean survival time | other | 1.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (sc) | mean survival time | other | 2.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (iv) | mean survival time | other | 0.12 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (iv) | mean survival time | other | 0.25 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (iv) | mean survival time | other | 0.5 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (iv) | mean survival time | other | 1.0 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (iv) | mean survival time | other | 2.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | median survival time | saline | 2.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | median survival time | saline | 4.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | median survival time | saline | 8.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | median survival time | saline | 16.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | mean survival time | sodium bicarbonate | 1.0 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | mean survival time | sodium bicarbonate | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | mean survival time | sodium bicarbonate | 4.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | mean survival time | sodium bicarbonate | 8.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | mean survival time | sodium bicarbonate | 16.0 mg/kg/injection | 91.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (oral) | mean survival time | sodium bicarbonate | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 3.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 3.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 181.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 181.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 5.0 mg/kg/injection | 198.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 5.0 mg/kg/injection | 198.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 204.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX006 (ip) | mean survival time | saline with Tween-80 | 6.0 mg/kg/injection | 204.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 0.12 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 0.25 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 0.4 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 0.5 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 0.5 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 0.5 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 0.5 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 0.8 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 1.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 1.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 1.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 1.0 mg/kg/injection | 135.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 1.6 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 2.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 2.0 mg/kg/injection | 175.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 2.0 mg/kg/injection | 250.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 2.0 mg/kg/injection | 160.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 2.4 mg/kg/injection | 250.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 3.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | median survival time | saline | 4.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 4.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.04 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.08 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.15 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.15 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.15 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 98.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.3 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.3 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.31 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.31 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.31 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 123.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 101.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 05/05 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 23; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.6 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.6 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.62 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.62 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 0.62 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 145.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 20; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 23; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 139.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 101.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 156.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 05/05 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 149.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 164.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 139.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 139.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 195.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 139.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 151.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 153.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.2 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 129.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 1.6 mg/kg/injection | 156.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 167.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 181.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 201.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 164.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 171.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 201.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 23; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 169.0 | Antitumor endpoint evaluated on day 20; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 256.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 87.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 186.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 221.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 224.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 223.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 218.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 186.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 215.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 230.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 261.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 234.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 198.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 170.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 207.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 206.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 167.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 180.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 164.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 184.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 182.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.4 mg/kg/injection | 163.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.4 mg/kg/injection | 222.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 3.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 93.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 93.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 23; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 89.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 167.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 167.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 98.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 93.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 87.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 4.8 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 98.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 92.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 00/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 9.6 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.05 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.13 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.13 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.25 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.25 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.5 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 0.63 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 30; 07/07 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 05/05 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 05/05 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 145.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 151.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 135.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 1.25 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 30; 07/07 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 164.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 193.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 164.0 | Antitumor endpoint evaluated on day 60; 09/09 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 2.5 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/07 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 145.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 4.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 0.25 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 0.25 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | water | 0.25 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 0.5 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 0.5 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 0.5 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | water | 1.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 1.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | water | 1.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 1.25 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 1.25 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 2.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 2.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 2.0 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on day 5 |
| Q01DX009 (ip) | mean survival time | water | 2.5 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 2.5 mg/kg/injection | 89.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 5.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | water | 5.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 0.25 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 0.31 mg/kg/injection | 113.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 0.5 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 0.62 mg/kg/injection | 127.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 1.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 1.25 mg/kg/injection | 187.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 2.0 mg/kg/injection | 171.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | other | 2.5 mg/kg/injection | 89.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (oral) | median survival time | saline | 2.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (oral) | median survival time | saline | 4.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (oral) | median survival time | saline | 8.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (oral) | median survival time | saline | 16.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 3.13 mg/kg/injection | 145.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 6.25 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 187.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 12.5 mg/kg/injection | 158.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 12.5 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 02/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 25.0 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 32.0 mg/kg/injection | 89.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 50.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 100.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 200.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline | 400.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 0.3 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 0.3 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 0.6 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 0.6 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 1.2 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 1.2 mg/kg/injection | 101.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 1.2 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 1.2 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 2.3 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 2.3 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 2.3 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 2.3 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 4.5 mg/kg/injection | 247.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 4.5 mg/kg/injection | 165.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 4.5 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 4.5 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 215.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX002 (ip) | mean survival time | saline with Tween-80 | 9.0 mg/kg/injection | 174.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 123.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 62; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 40; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 66; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 1.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 40; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 66; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 62; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 2.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 40; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 165.0 | Antitumor endpoint evaluated on day 66; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 62; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 4.0 mg/kg/injection | 159.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 205.0 | Antitumor endpoint evaluated on day 40; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 66; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 62; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | median survival time | saline | 8.0 mg/kg/injection | 202.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 0.63 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 60; 09/09 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 0.78 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.25 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.56 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 1.56 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 123.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 123.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 152.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 108.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 117.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 125.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 2.5 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 3.13 mg/kg/injection | 211.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 3.13 mg/kg/injection | 146.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 151.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 141.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 153.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 164.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 187.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 156.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 138.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 145.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 138.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 136.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 190.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 151.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 163.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 177.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 149.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 198.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 151.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 201.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 159.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 159.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 139.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 157.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 160.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 158.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 5.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 6.25 mg/kg/injection | 251.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 6.25 mg/kg/injection | 160.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 189.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 210.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 288.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 180.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 218.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 188.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 187.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 118.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 232.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 153.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 213.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 8.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 92.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 101.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 88.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 00/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 169.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 10.0 mg/kg/injection | 184.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 12.5 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 12.5 mg/kg/injection | 87.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 98.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 91.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 02/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 178.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 89.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 00/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 00/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 02/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/04 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 25.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 60; 05/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 25.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.25 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.25 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.25 mg/kg/injection | 142.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.25 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.25 mg/kg/injection | 134.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 1.5 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 2.0 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 2.0 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 2.5 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 2.5 mg/kg/injection | 145.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 2.5 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 2.5 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 2.5 mg/kg/injection | 162.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 3.0 mg/kg/injection | 114.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 4.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 4.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 5.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 5.0 mg/kg/injection | 103.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 5.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 5.0 mg/kg/injection | 131.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 5.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 5.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 5.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 6.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 8.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 8.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 10.0 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 10.0 mg/kg/injection | 91.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 12.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 16.0 mg/kg/injection | 73.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 02/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 20.0 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 00/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | water | 24.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | other | 1.0 mg/kg/injection | 128.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | other | 2.0 mg/kg/injection | 136.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | other | 4.0 mg/kg/injection | 160.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | other | 8.0 mg/kg/injection | 93.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | dextrose | 1.0 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | dextrose | 2.0 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | dextrose | 4.0 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 30; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | dextrose | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | dextrose | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 00/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | dextrose | 32.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 01/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (oral) | median survival time | saline | 2.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (oral) | median survival time | saline | 4.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (oral) | median survival time | saline | 8.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (oral) | median survival time | saline | 16.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q04DX009 (ip) | mean survival time | saline | 0.25 mg/kg/injection | 101.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q04DX009 (ip) | mean survival time | saline | 0.5 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q04DX009 (ip) | mean survival time | saline | 1.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q04DX009 (ip) | mean survival time | saline | 2.0 mg/kg/injection | 173.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q04DX009 (ip) | mean survival time | saline | 4.0 mg/kg/injection | 156.0 | Antitumor endpoint evaluated on day 30; 06/06 animals surviving on day 5 |
| Q07DX004 (ip) | median survival time | saline | 3.0 mg/kg/injection | 123.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 3.0 mg/kg/injection | 119.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 3.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 3.0 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 5.0 mg/kg/injection | 148.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 5.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 5.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 5.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 8.4 mg/kg/injection | 189.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 8.4 mg/kg/injection | 188.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 8.4 mg/kg/injection | 188.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 8.4 mg/kg/injection | 194.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 14.0 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 14.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 14.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 7; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX004 (ip) | median survival time | saline | 14.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X003 (ip) | mean survival time | water | 1.0 mg/kg/injection | 126.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X003 (ip) | mean survival time | water | 2.0 mg/kg/injection | 140.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X003 (ip) | mean survival time | water | 4.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X003 (ip) | mean survival time | water | 8.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X003 (ip) | mean survival time | water | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |