| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 1.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 1.5 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 1.5 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 2.25 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 2.25 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 3.37 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 3.37 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 5.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 5; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 5.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 45; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 7.5 mg/kg/injection | 135.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX005 (ip) | mean survival time | saline with Tween-80 | 7.5 mg/kg/injection | 135.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on tox evaluation day (usually day 5) |