| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 54.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 84.0 | Antitumor endpoint evaluated on day 11; 02/02 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 65.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 77.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 49.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 21.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/01 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 63.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 64.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 41.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 12.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 48.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 34.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 33.0 | Antitumor endpoint evaluated on day 11; 02/02 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 25.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/02 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 11.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 1.0 | Antitumor endpoint evaluated on day 11; 02/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 4.0 | Antitumor endpoint evaluated on day 11; 02/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/02 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 68.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 52.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 80.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | 39.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | 67.0 | Antitumor endpoint evaluated on day 11; 05/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 16.0 mg/kg/injection | 48.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 16.0 mg/kg/injection | 37.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 1.0 mg/kg/injection | 82.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 2.0 mg/kg/injection | 68.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 4.0 mg/kg/injection | 62.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 8.0 mg/kg/injection | 16.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 2.0 mg/kg/injection | 46.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 4.0 mg/kg/injection | 56.0 | Antitumor endpoint evaluated on day 11; 05/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 8.0 mg/kg/injection | 21.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 16.0 mg/kg/injection | 26.0 | Antitumor endpoint evaluated on day 11; 04/06 animals surviving on day 11 |