In Vivo Screening Data Summary

NCI In Vivo Screening Data

Lewis Lung Carcinoma (intramuscular) in C57BL/6 mice

NSC 119875
CAS 15663-27-1
Cisplatin; Plantinol AQ; Cis-DDP

Chemical Data
Schedule (route) Endpoint Vehicle Dose Treated/Control (%) Observations
Q01DX011 (ip) median survival time saline 1.0 mg/kg/injection 111.0 Antitumor endpoint evaluated on day 60; 06/06 animals surviving on tox evaluation day (usually day 5)
Q01DX011 (ip) median survival time saline 2.0 mg/kg/injection 0.0 Antitumor endpoint evaluated on day 60; 06/06 animals surviving on tox evaluation day (usually day 5)
Q01DX011 (ip) median survival time saline 4.0 mg/kg/injection 0.0 Antitumor endpoint evaluated on day 60; 06/06 animals surviving on tox evaluation day (usually day 5)