| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 28.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 23.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 39.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 53.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 13.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | -23.0 | Antitumor endpoint evaluated on day 11; 02/02 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 11.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 1.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 26.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 13.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | -4.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | -23.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | -88.0 | Antitumor endpoint evaluated on day 11; 02/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | -59.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | -60.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | -72.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | -46.0 | Antitumor endpoint evaluated on day 11; 02/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -51.0 | Antitumor endpoint evaluated on day 11; 02/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -100.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -100.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | 2.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -86.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | -98.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | 1.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 8.0 mg/kg/injection | -100.0 | Antitumor endpoint evaluated on day 11; 04/04 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 16.0 mg/kg/injection | -96.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 16.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 02/04 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 16.0 mg/kg/injection | -66.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 1.0 mg/kg/injection | 41.0 | Antitumor endpoint evaluated on day 11; 03/04 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 2.0 mg/kg/injection | 35.0 | Antitumor endpoint evaluated on day 11; 04/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 4.0 mg/kg/injection | 7.0 | Antitumor endpoint evaluated on day 11; 05/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 8.0 mg/kg/injection | -99.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 2.0 mg/kg/injection | 42.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 4.0 mg/kg/injection | 28.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 8.0 mg/kg/injection | 1.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | suspension in saline | 16.0 mg/kg/injection | -10.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |