| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX010 (ip) | mean tumor weight change | saline | 0.5 mg/kg/injection | 40.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (ip) | mean tumor weight change | saline | 1.0 mg/kg/injection | 11.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (ip) | mean tumor weight change | saline | 2.0 mg/kg/injection | -22.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (ip) | mean tumor weight change | saline | 4.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 01/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 40.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 0.5 mg/kg/injection | 59.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | 3.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 1.0 mg/kg/injection | -43.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | -59.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 2.0 mg/kg/injection | -20.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -77.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q01DX010 (sc) | mean tumor weight change | saline | 4.0 mg/kg/injection | -91.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q04DX003 (ip) | mean tumor weight change | saline | 1.66 mg/kg/injection | 8.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q04DX003 (ip) | mean tumor weight change | saline | 2.0 mg/kg/injection | 5.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (ip) | mean tumor weight change | saline | 3.33 mg/kg/injection | 3.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q04DX003 (ip) | mean tumor weight change | saline | 4.0 mg/kg/injection | -92.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (ip) | mean tumor weight change | saline | 6.65 mg/kg/injection | -34.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q04DX003 (ip) | mean tumor weight change | saline | 8.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 04/06 animals surviving on day 11 |
| Q04DX003 (ip) | mean tumor weight change | saline | 13.3 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 1.66 mg/kg/injection | 21.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 3.33 mg/kg/injection | 6.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 6.65 mg/kg/injection | -36.0 | Antitumor endpoint evaluated on day 11; 03/03 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline | 13.3 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 11; 00/03 animals surviving on day 11 |