| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX004 (ip) | median survival time | saline | 2.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q01DX004 (ip) | median survival time | saline | 2.0 mg/kg/injection | 95.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q01DX004 (ip) | median survival time | saline | 2.0 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q01DX004 (ip) | median survival time | saline | 3.0 mg/kg/injection | 111.0 | Antitumor endpoint evaluated on day 60; 07/08 animals surviving on day 10 |
| Q01DX004 (ip) | median survival time | saline | 3.0 mg/kg/injection | 98.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q01DX004 (ip) | median survival time | saline | 3.0 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q01DX004 (ip) | median tumor weight (est.) | saline | 2.0 mg/kg/injection | 58.0 | Antitumor endpoint evaluated on day 20; 08/08 animals surviving on day 20 |
| Q01DX004 (ip) | median tumor weight (est.) | saline | 2.0 mg/kg/injection | 132.0 | Antitumor endpoint evaluated on day 19; 08/08 animals surviving on day 19 |
| Q01DX004 (ip) | median tumor weight (est.) | saline | 3.0 mg/kg/injection | 47.0 | Antitumor endpoint evaluated on day 20; 08/08 animals surviving on day 20 |
| Q01DX004 (ip) | median tumor weight (est.) | saline | 3.0 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 19; 08/08 animals surviving on day 19 |
| Q03DX002 (ip) | median survival time | saline | 4.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q03DX002 (ip) | median survival time | saline | 4.0 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q03DX002 (ip) | median survival time | saline | 4.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q03DX002 (ip) | median survival time | saline | 6.0 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q03DX002 (ip) | median survival time | saline | 6.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q03DX002 (ip) | median survival time | saline | 6.0 mg/kg/injection | 86.0 | Antitumor endpoint evaluated on day 60; 08/08 animals surviving on day 10 |
| Q03DX002 (ip) | median tumor weight (est.) | saline | 4.0 mg/kg/injection | 50.0 | Antitumor endpoint evaluated on day 20; 08/08 animals surviving on day 20 |
| Q03DX002 (ip) | median tumor weight (est.) | saline | 4.0 mg/kg/injection | 213.0 | Antitumor endpoint evaluated on day 19; 08/08 animals surviving on day 19 |
| Q03DX002 (ip) | median tumor weight (est.) | saline | 6.0 mg/kg/injection | 40.0 | Antitumor endpoint evaluated on day 20; 08/08 animals surviving on day 20 |
| Q03DX002 (ip) | median tumor weight (est.) | saline | 6.0 mg/kg/injection | 127.0 | Antitumor endpoint evaluated on day 19; 08/08 animals surviving on day 19 |