| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 3.5 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 8 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 5.3 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 8 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 8.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 45; 07/07 animals surviving on day 7 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 8.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 45; 06/06 animals surviving on day 8 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 8.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on day 8 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 10.0 mg/kg/injection | 112.0 | Antitumor endpoint evaluated on day 45; 07/07 animals surviving on day 7 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 12.0 mg/kg/injection | 121.0 | Antitumor endpoint evaluated on day 45; 07/07 animals surviving on day 7 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 12.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on day 8 |
| Q01DX001 (ip) | median survival time | saline with Tween-80 | 18.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 45; 10/10 animals surviving on day 8 |
| Q04DX003 (ip) | median survival time | saline with Tween-80 | 2.3 mg/kg/injection | 105.0 | Antitumor endpoint evaluated on day 30; 01/07 animals surviving on day 8 |
| Q04DX003 (ip) | median survival time | saline with Tween-80 | 3.5 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 02/07 animals surviving on day 8 |
| Q04DX003 (ip) | median survival time | saline with Tween-80 | 5.3 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 30; 02/07 animals surviving on day 8 |
| Q04DX003 (ip) | median survival time | saline with Tween-80 | 8.0 mg/kg/injection | 153.0 | Antitumor endpoint evaluated on day 30; 06/07 animals surviving on day 8 |