| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX005 (ip) | median survival time | saline | 1.25 mg/kg/injection | 87.0 | Antitumor endpoint evaluated on day 75; 10/10 animals surviving on day 5 |
| Q01DX005 (ip) | median survival time | saline | 2.5 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 75; 09/09 animals surviving on day 5 |
| Q01DX005 (ip) | median survival time | saline | 5.0 mg/kg/injection | 93.0 | Antitumor endpoint evaluated on day 75; 10/10 animals surviving on day 5 |
| Q01DX005 (ip) | median survival time | saline | 10.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 75; 10/10 animals surviving on day 5 |
| Q01DX005 (ip) | median survival time | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 75; 06/10 animals surviving on day 5 |