| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q04DX003 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 5.0 | Antitumor endpoint evaluated on day 12; 05/06 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 12; 06/06 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 2.5 mg/kg/injection | 14.0 | Antitumor endpoint evaluated on day 12; 05/05 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 2.0 | Antitumor endpoint evaluated on day 12; 06/06 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | -16.0 | Antitumor endpoint evaluated on day 12; 06/06 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 5.0 mg/kg/injection | 3.0 | Antitumor endpoint evaluated on day 12; 04/04 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -12.0 | Antitumor endpoint evaluated on day 12; 06/06 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -29.0 | Antitumor endpoint evaluated on day 12; 05/05 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 10.0 mg/kg/injection | -36.0 | Antitumor endpoint evaluated on day 12; 04/06 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 12; 02/06 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 12; 00/05 animals surviving on day 12 |
| Q04DX003 (ip) | mean tumor weight change | saline | 20.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 12; 00/06 animals surviving on day 12 |