| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 300.0 mg/kg/injection | 148.0 | Antitumor endpoint evaluated on day 11; 05/05 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 600.0 mg/kg/injection | 115.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 1200.0 mg/kg/injection | 76.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |
| Q04DX003 (sc) | mean tumor weight change | saline with Tween-80 | 2400.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 11; 06/06 animals surviving on day 11 |