| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX001 (ip) | mean survival time | Klucel (hydroxypropylcellulose) (HPC) | 100.0 mg/kg/injection | 91.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | Klucel (hydroxypropylcellulose) (HPC) | 200.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | Klucel (hydroxypropylcellulose) (HPC) | 400.0 mg/kg/injection | 88.0 | Antitumor endpoint evaluated on day 30; 03/03 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 100.0 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 20; 05/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 200.0 mg/kg/injection | 107.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | mean survival time | saline with Tween-80 | 400.0 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline with Tween-80 | 100.0 mg/kg/injection | 94.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline with Tween-80 | 200.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline with Tween-80 | 400.0 mg/kg/injection | 96.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |