| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q04DX003 (ip) | mean survival time | saline with Tween-80 | 100.0 mg/kg/injection | 97.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline with Tween-80 | 200.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q04DX003 (ip) | mean survival time | saline with Tween-80 | 400.0 mg/kg/injection | 90.0 | Antitumor endpoint evaluated on day 20; 06/06 animals surviving on tox evaluation day (usually day 5) |