| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX010 (ip) | median survival time | saline | 3.13 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX010 (ip) | median survival time | saline | 3.13 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX010 (ip) | median survival time | saline | 6.25 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX010 (ip) | median survival time | saline | 6.25 mg/kg/injection | 123.0 | Experiment continued until the death of all animals; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX010 (ip) | median survival time | saline | 12.5 mg/kg/injection | 114.0 | Experiment continued until the death of all animals; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX010 (ip) | median survival time | saline | 12.5 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 06/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX010 (ip) | median survival time | saline | 25.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 04/06 animals surviving on tox evaluation day (usually day 5) |
| Q01DX010 (ip) | median survival time | saline | 25.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 00/06 animals surviving on tox evaluation day (usually day 5) |