| Schedule (route) | Endpoint | Vehicle | Dose | Treated/Control (%) | Observations |
|---|---|---|---|---|---|
| Q01DX001 (ip) | median survival time | saline | 60.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 90.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 120.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | median survival time | saline | 240.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 60.0 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 60.0 mg/kg/injection | 106.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 90.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 90.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 120.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 120.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 240.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (ip) | mean survival time | saline | 240.0 mg/kg/injection | 116.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 39.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 65.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 65.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 108.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 108.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 180.0 mg/kg/injection | 126.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 180.0 mg/kg/injection | 121.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 300.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 05/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 300.0 mg/kg/injection | 126.0 | Experiment continued until the death of all animals; 06/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX001 (sc) | median survival time | other | 500.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 02/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 60.0 mg/kg/injection | 144.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 60.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 60.0 mg/kg/injection | 147.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 90.0 mg/kg/injection | 166.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 90.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 90.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 120.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 30; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 120.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 120.0 mg/kg/injection | 161.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 240.0 mg/kg/injection | 0.0 | Antitumor endpoint evaluated on day 30; 05/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 240.0 mg/kg/injection | 73.0 | Antitumor endpoint evaluated on day 8; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | saline | 240.0 mg/kg/injection | 73.0 | Antitumor endpoint evaluated on day 5; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | other | 10.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 38; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | other | 20.0 mg/kg/injection | 137.0 | Antitumor endpoint evaluated on day 38; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | other | 40.0 mg/kg/injection | 168.0 | Antitumor endpoint evaluated on day 38; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (ip) | median survival time | other | 80.0 mg/kg/injection | 150.0 | Antitumor endpoint evaluated on day 38; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (sc) | median survival time | other | 5.0 mg/kg/injection | 109.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (sc) | median survival time | other | 10.0 mg/kg/injection | 113.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (sc) | median survival time | other | 20.0 mg/kg/injection | 124.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (sc) | median survival time | other | 40.0 mg/kg/injection | 143.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (sc) | median survival time | other | 80.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX009 (sc) | median survival time | other | 160.0 mg/kg/injection | 102.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX012 (ip) | median survival time | other | 12.5 mg/kg/injection | 122.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX012 (ip) | median survival time | other | 25.0 mg/kg/injection | 133.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX012 (ip) | median survival time | other | 50.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX012 (ip) | median survival time | other | 100.0 mg/kg/injection | 138.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX012 (ip) | median survival time | other | 200.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 30; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (ip) | median survival time | other | 14.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (ip) | median survival time | other | 23.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (ip) | median survival time | other | 39.0 mg/kg/injection | 110.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (ip) | median survival time | other | 65.0 mg/kg/injection | 170.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (ip) | median survival time | other | 108.0 mg/kg/injection | 155.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 14.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 14.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 14.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 40; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 23.0 mg/kg/injection | 100.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 23.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 23.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 23.0 mg/kg/injection | 95.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 23.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 23.0 mg/kg/injection | 120.0 | Antitumor endpoint evaluated on day 40; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 28.0 mg/kg/injection | 110.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 38.9 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 38.9 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 104.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 130.0 | Antitumor endpoint evaluated on day 40; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 110.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 155.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 94.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 46.8 mg/kg/injection | 129.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 47.0 mg/kg/injection | 110.0 | Experiment continued until the death of all animals; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 64.8 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 64.8 mg/kg/injection | 172.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 136.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 173.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 120.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 170.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 166.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 165.0 | Antitumor endpoint evaluated on day 40; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 78.0 mg/kg/injection | 158.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 78.0 mg/kg/injection | 155.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 154.0 | Antitumor endpoint evaluated on day 60; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 90.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 168.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 180.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 177.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 159.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 155.0 | Antitumor endpoint evaluated on day 40; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 130.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 130.0 mg/kg/injection | 165.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 110.0 | Antitumor endpoint evaluated on day 40; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 154.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 02/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 157.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 142.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 144.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 155.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 216.0 mg/kg/injection | 133.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 216.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 140.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 127.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 06/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 04/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 130.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 5.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 04/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 8.4 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 8.4 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 03/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 8.4 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 01/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 8.4 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 10.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 14.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 14.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 06/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 14.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 00/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 14.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 06/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 17.0 mg/kg/injection | 110.0 | Experiment continued until the death of all animals; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 17.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 23.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 06/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 23.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 03/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 23.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 23.3 mg/kg/injection | 145.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 28.0 mg/kg/injection | 135.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 28.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 38.9 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 38.9 mg/kg/injection | 145.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 39.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 06/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 39.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 02/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 39.0 mg/kg/injection | 136.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 47.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 47.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 64.8 mg/kg/injection | 145.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 64.8 mg/kg/injection | 140.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 65.0 mg/kg/injection | 145.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 65.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 02/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 65.0 mg/kg/injection | 154.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 78.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 78.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 130.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 145.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 155.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 140.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 127.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 130.0 mg/kg/injection | 140.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 130.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 180.0 mg/kg/injection | 120.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 180.0 mg/kg/injection | 131.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 180.0 mg/kg/injection | 155.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 216.0 mg/kg/injection | 130.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 216.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 300.0 mg/kg/injection | 120.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (sc) | median survival time | methylcellulose (MC) | 300.0 mg/kg/injection | 127.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | other | 65.0 mg/kg/injection | 175.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | other | 108.0 mg/kg/injection | 165.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | other | 180.0 mg/kg/injection | 140.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | other | 300.0 mg/kg/injection | 135.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | other | 500.0 mg/kg/injection | 120.0 | Experiment continued until the death of all animals; 07/08 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 8.4 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 04/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 14.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 14.0 mg/kg/injection | 104.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 17.0 mg/kg/injection | 95.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 23.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 23.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 00/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 23.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 28.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 39.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 05/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 39.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 00/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 39.0 mg/kg/injection | 104.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 47.0 mg/kg/injection | 104.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 65.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 65.0 mg/kg/injection | 104.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 65.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 01/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 78.0 mg/kg/injection | 113.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 01/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 108.0 mg/kg/injection | 118.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 130.0 mg/kg/injection | 136.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 180.0 mg/kg/injection | 140.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 180.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 180.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 03/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 216.0 mg/kg/injection | 109.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 300.0 mg/kg/injection | 150.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 300.0 mg/kg/injection | 154.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 300.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 05/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 360.0 mg/kg/injection | 122.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 500.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 05/10 animals surviving on tox evaluation day (usually day 5) |
| Q01DX Z (oral) | median survival time | methylcellulose (MC) | 500.0 mg/kg/injection | 140.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 0.65 mg/kg/injection | 116.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 23.0 mg/kg/injection | 94.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 177.0 | Experiment continued until the death of all animals; 09/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 189.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 152.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 166.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 168.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 166.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 06/10 animals surviving on tox evaluation day (usually day 5) |
| Q02DX Z (sc) | median survival time | other | 500.0 mg/kg/injection | 127.0 | Experiment continued until the death of all animals; 08/10 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 39.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 65.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 108.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 121.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 180.0 mg/kg/injection | 126.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 121.0 | Experiment continued until the death of all animals; 07/10 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 300.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 05/08 animals surviving on tox evaluation day (usually day 5) |
| Q07DX Z (sc) | median survival time | other | 500.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 01/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 5.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 8.4 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 8.4 mg/kg/injection | 168.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 14.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 14.0 mg/kg/injection | 168.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 23.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 23.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 39.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 39.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 65.0 mg/kg/injection | 136.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 65.0 mg/kg/injection | 100.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 108.0 mg/kg/injection | 126.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 108.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 180.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 180.0 mg/kg/injection | 126.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 300.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 04/10 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 300.0 mg/kg/injection | 157.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q## X Z (sc) | median survival time | other | 500.0 mg/kg/injection | 0.0 | Experiment continued until the death of all animals; 04/10 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 14.0 mg/kg/injection | 115.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 14.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 23.0 mg/kg/injection | 163.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 23.0 mg/kg/injection | 105.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 39.0 mg/kg/injection | 157.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 39.0 mg/kg/injection | 110.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 65.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 65.0 mg/kg/injection | 173.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 108.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 108.0 mg/kg/injection | 157.0 | Experiment continued until the death of all animals; 08/08 animals surviving on tox evaluation day (usually day 5) |
| Q#A X Z (sc) | median survival time | other | 180.0 mg/kg/injection | 147.0 | Experiment continued until the death of all animals; 10/10 animals surviving on tox evaluation day (usually day 5) |