Graph showing Tumor weight versus days since subcutaneous implant of the KM-12 tumor in nu/nu NCr mice.
There were five groups in the study.
Group 1: 1x10^7 cells were implanted SC. 80% Take Rate.
Group 2: 5x10^6 cells were implanted SC. 100% Take Rate.
Group 3: 1x10^6 cells were implanted SC. 70% Take Rate.
Group 4: 5x10^5 cells were implanted SC. 30% Take Rate.
Group 5: 1x10^5 cells were implanted SC. 10% Take Rate.
NOTES: Ten animals were assigned to each group.
Starting at Day 22, animals in various groups that had reached endpoint were removed from the study resulting in fluctuations 
in the growth curves at subsequent time points. Growth curves were no longer calculated when <70% remained in the group.
Group 1 Notes: On Day 13, two animals that had reached endpoint were removed from the study [the take rate was adjusted accordingly].
Group 3 Notes: Three animals failed to establish tumor growth post inoculation.
Group 4 Notes: Seven animals failed to establish tumor growth post inoculation.
Group 5 Notes: Nine animals failed to establish tumor growth post inoculation. One animal demonstrated slight tumor growth starting on
Day 22 with a final measurement of ~200 mg on Day 29.