Graph showing Tumor weight versus days since subcutaneous implant of the SK-MEL-5 tumor in nu/nu NCr mice. There were three groups in the study. Group 1: 1x10^7 cells were implanted SC Bilaterally [Passage 1]. 100% Take Rate. Group 2: fragments implanted bilaterally- Passage 4. 100% Take Rate. Group 3: fragments implanted bilaterally- Passage 10. 100% Take Rate. Animals were bilaterally implanted for subsequent tumor collection and microarray studies. To ensure standardization in data reporting, only right tumor values were utilized for growth data associated with microarray studies. P1 [Group 1] Notes: Ten animals were assigned to this group. P4 [Group 2] Notes: Eight animals were assigned to this group. P10 [Group 3] Notes: Eight animals were assigned to this group.