DTP Branches
and Offices
Last Updated: 04/02/15
TPB Publications
1994 Abstracts/Presentations
- Tomaszewski, J.E., 1994. Safety and Toxicity Evaluation of Recombinant and Synthetic Vaccine Products: The NCI Experience. BioEast 94, Session 5D, p 35. Washington, D.C.
- Agbaria, R., H. Ford, Jr., J.A. Kelley, A. Koester, V. Moore, C.R. Hassler, J.E. Tomaszewski and S.J. Donohue, 1994. Continuous Infusion of Cyclopentenyl Cytosine (NSC-375575) in Beagle Dogs with Hemodynamic and Pharmacologic Monitoring. [Abstract No. 2752]. Proc. Amer. Assoc. Cancer Res., 35, 461.
- Benvenuto, J.A., L.A. Zwelling, W.N. Hittelman, W. Plunkett, D. Farquhar and R.A. Newman, 1994. Preclinical Pharmacology Studies of Penclomedine (NSC 338720), [Abstract No. 2303]. Proc. Amer. Assoc. Cancer Res., 35, 386.
- Bigelow, J., L. Chrin, P. Horton, L. Mathews and J. McCormack, 1994. Analytical and Pharmacokinetic Studies of a Quinocarmycin Derivative, [Abstract No. 2545]. Proc. Amer. Assoc. Cancer Res., 35, 427.
- Bigelow, J., L. Mathews, L. Chrin, P. Horton and J. McCormack, 1994. Analytical Studies and Murine Pharmacokinetics of Cosalane, [Abstract No. 2546]. Proc. Amer. Assoc. Cancer Res., 35, 427.
- Egorin, M.J., D.M. Rosen, M.A. Simon, M.F. Ballesteros, E. Dixon and S.S. Pan, 1994. Cellular Accumulation of Chloroquinoxaline Sulfonamide (CQS), [Abstract No. 2334]. Proc. Amer. Assoc. Cancer Res., 35, 392.
- Egorin, M.J., Z.M. Yuan, D.L. Sentz, N.D. Eddington and J.L. Eiseman, 1994. Plasma Pharmacokinetics (pk) in CD2F1 Mice of the Polyamine Analog (BE-4444) (NSC D640506), [Abstract No. 2557]. Proc. Amer. Assoc. Cancer Res., 35, 429.
- Evans, E., R. Kovatch, R. Lopez, J. Baker, B. Mowry, D. Smith, D. Arneson, R. Gatz, M. McDermott and J.E. Tomaszewski, 1994. Five Daily Dose Toxicity of Bizelesin (NSC-615291) in Fischer 344 Rats and Beagle Dogs. [Abstract No. 2750]. Proc. Amer. Assoc. Cancer Res., 35, 461.
- Hill, J.R., J.E. Schindler-Horvat, R.C. Baldwin, J.T. MacGregor, B.L. Osborn, S.J. Donohue and C.A. Tyson, 1994. Toxicity of Ecteinascidin 729 (NSC-638718) in CD2F1 Mice and Beagle Dogs, [Abstract No. 2789]. Proc. Amer. Assoc. Cancer Res., 35, 467.
- May, R.D., M.J. Murphy, Jr., C.L. Erickson-Miller, J.E. Tomaszewski, B.L. Osborn and J.G. Page, 1994. Myelotoxicity Evaluation of Dolastatin 10 (NSC-376128) and Swainsonine (NSC-614553) Using Murine, Canine and Human In Vitro CFUGM Assays. [Abstract No. 2398]. Proc. Amer. Assoc. Cancer Res., 35, 402.
- Newman, R.A., M. Costa and A. Fuentes, 1994. Analytical Assay Development for Costatolide (NSC 661122) and 7,8-Dihydrocostatolide (NSC 661123), Potential Anti-HIV Agents, [Abstract No. 2526]. Proc. Amer. Assoc. Cancer Res., 35, 424.
- Placke, M.E., D.C. Emmerling, M.E. Lynch, S.W. Graves, P.J. Tosca, J.T. Yarrington and J.E. Tomaszewski, 1994. Toxicity of Protease Inhibitor KNI-272 in Rats and Dogs Following Continuous Intravenous Infusion or Repeated IV Treatment. [Abstract No. 2751]. Proc. Amer. Assoc. Cancer Res., 35, 461.
- Placke, M.E., R.R. Moutvic, A.W. Singer, L.H. Pai, Q-c Wang, I. Pastan and J.E. Tomaszewski, 1994. Pharmacokinetics and Toxicity Evaluations of the Recombinant Immunotoxin LMB-7 [B3(Fv)-PE38] in Cynomolgus Monkeys. [Abstract No. 2413]. Proc. Amer. Assoc. Cancer Res., 35, 405.
- Page, J.G., H.D. Giles, S.L. Gerson, A.C. Smith and J.E. Tomaszewski, 1994. Preclinical Toxicity Study of O6-Benzylguanine (NSC-637037) and BCNU (Carmustine, NSC-409962) in Male and Female Beagle Dogs. [Abstract No.1952]. Proc. Amer. Assoc. Cancer Res., 35, 328.
- Reid, J.M., D.L. Walker, S. Naylor, L.H. Benson and M.M. Ames, 1994. Murine Metabolism of Pyrazoloacridine (NSC-366140): Identification and Cytotoxicity of the Urinary Metabolites 9-Desmethylpyrazoloacridine and pyrazoloacridine N-Oxide, [Abstract No. 2512]. Proc. Amer. Assoc. Cancer Res., 35, 421.
- Rodman, L.E., H.D. Giles, J.E. Tomaszewski, A.C. Smith, B.L. Osborn and J.G. Page, 1994. Preclinical Toxicology Study of O6-Benzylguanine (NSC-637037) and 1,3-Bis(2-chloroethyl)-1-nitrosourea (NSC-409962) in Mice. [Abstract No. 1954]. Proc. Amer. Assoc. Cancer Res., 35, 328.
- Rogers, T.S., L.E. Rodman, J.E. Tomaszewski, B.L. Osborn and J.G. Page, 1994. Preclinical Toxicology and Pharmacokinetic Studies of O6-Benzyl-guanine (NSC-637037) in Mice and Dogs. [Abstract No. 1953]. Proc. Amer. Assoc. Cancer Res., 35, 328.
- Schindler-Horvat, J.E., J.R. Hill, S.J. Donohue, B.L. Osborn and C.A. Tyson, 1994. Species Comparison of Toxicity of Dolastatin 10 in CD2F1 Mice and Beagle Dogs, [Abstract No. 2790]. Proc. Amer. Assoc. Cancer Res., 35, 468.
- Smith, A.C., L. Rubinstein, A. Koutsoukos, M. Christian, C.K. Grieshaber, J.E. Tomaszewski and M.R. Grever, 1994. Evaluation of Preclinical Toxicity Models for Phase I Clinical Trials of Anticancer Drugs. [Abstract No. 2741]. Proc. Amer. Assoc. Cancer Res., 35, 459.
- Walker, D.L., J.M. Reid and M.M. Ames, 1994. Preclinical Pharmacology of the Potent Marine Natural Product, Ecteinascidin 729 (NSC-638718), [Abstract No. 2511]. Proc. Amer. Assoc. Cancer Res., 35, 421.
- Yuan, Z., J. Eisman, K. Plaisance, D. Sentz, S. Bigora, M. Fossler, D. Young and M. Egorin, 1994. Plasma Pharmacokinetics (PK) of Butyrate after the Administration of Tributyrin & Na Butyrate to Mice & Rats, [Abstract No. 2556]. Proc. Amer. Assoc. Cancer Res., 35, 424.
- Garg, A., J.E. Tomaszewski, E. Barbera-Guillem and M.J. Murphy, Jr., 1994. In Vitro Bone Marrow Toxicity of the Antineoplastic Drug, Bizelesin (NSC-615921). ISEH Abstract No. 133. 23rd Annual Meeting, International Society for Experimental Hematology. Minneapolis, MN.
- Trang, J.M., L.E. Rodman, J.F. Martin, A.C. Smith, J.E. Tomaszewski and J.G. Page, 1994. Pharmacokinetics and Dose Range-Finding of O6-Benzylguanine (NSC-637037) in Beagle Dogs Following Single-Dose IV Administration. American Association of Pharmaceutical Scientists (AAPS) Meeting.
- Trang, J.M., L.E. Rodman, J.F. Martin, A.C. Smith, J.E. Tomaszewski and J.G. Page, 1994. Pharmacokinetics of O6-Benzylguanine (O6BG) in Combination with 1,3-Bis(2-Chloroethyl)-1-nitrosourea (BCNU) in Beagle Dogs. American Association of Pharmaceutical Scientists (AAPS) Meeting.
- Garg, A., J.E. Tomaszewski, E. Barbera-Guillem and M.J. Murphy, Jr., 1994. In Vitro Bone Marrow Toxicity of Flavopiridol (NSC-649890) to Human, Canine and Murine Hematopoietic Progenitor Cells. 36th Annual Meeting, American Society of Hematology. Nashville, TN.
- Volpe, D.A., J.E. Tomaszewski, R.E. Parchment, A. Garg, K.P. Flora, M.J. Murphy and C.K. Grieshaber, 1994. Myelotoxic Effects of Bizelesin to Human, Canine and Murine Myeloid Progenitor Cells In Vitro. FDA Science Forum. Washington, DC.
- Fukazawa, T., N. Takeuchi, N. Fujisawa, N. Hattori, T. Mimoto, S. Abe, K. Yuki, Y. Kiso, J. Tomaszewski, H. Hayashi and H. Mitsuya, 1994. KNI-272: A Potent HIV Protease Inhibitor Exhibiting a Favorable Oral Bioavailability in Beagle Dogs. [Abstract No. PB0841, p. 207]. Tenth International Conference on AIDS. Yokohama, Japan.
About the Branch Chief
For information regarding the TPB, please contact Dr. Jerry M. Collins, Associate Director, collinsje@mail.nih.gov