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Developmental Therapeutics Program (DTP)
Last Updated: 04/02/15

TPB Publications

1999 Abstracts/Presentations

  1. Jenta T, Soejarto, D, Buckheit, R, Arnold, E, Schweikart, K, and Covey, J. 1999. (-)-Calanolide B - A Novel and Naturally-occurring Non-nucleoside Reverse Transcriptase Inhibitor of HIV-1. 6th Conference on Retroviruses and Opportunistic Infections.
  2. Brown, A.P., R.L. Morrissey, S.J. Donohue, B.R. Vishnuvajjala, J.E. Tomaszewski, and B.S. Levine, 1999. 8-Chloro-cyclic AMP, but not 2-Fluoro-8-chloro-cyclic AMP Is Nephrotoxic in Mice [Abstract No. 135]. The Toxicologist, 48 (1-S): 29.
  3. Hassler, C.R., R.I. Hamlin, N.A. Turner, K.M. Schweikart and J.E. Tomaszewski, 1999. Cardiotoxicity of Neriifolin (NSC 123976) in Beagle Dogs [Abstract No. 1394]. The Toxicologist, 48 (1-S): 295.
  4. Smith, A.C., C.J.G. Chang, R.B. Thompson, J.E. Tomaszewski and J.G. Page, 1999. The Effect of O6Benzylguanine Pretreatment on BCNU-Induced Pulmonary Toxicity [Abstract No. 1534]. The Toxicologist, 48 (1-S): 325.
  5. Bigelow, J., Mathews, L., McCormack, J. 1999. Analytical and Pharmacokinetic Studies of a Trichothecene Derivative with Antitumor Activity. [Abstract No. 2581]. Proc. Amer. Assoc. Cancer Res., 40, 390.
  6. Bigelow, J., Mathews, L., McCormack, J. 1999. Analytical and Pharmacokinetic Studies of a Steroid Glycoside with Antineoplastic Activity. [Abstract No. 2580]. Proc. Amer. Assoc. Cancer Res., 40, 390.
  7. Chan, K.K., Jiang, C., Covey, J. 1999. Pharmacokinetics of 6-Hydroxydopamine in the Rat with and Without Tempol, the Stable Free Radical. [Abstract No. 2595]. Proc. Amer. Assoc. Cancer Res., 40, 392.
  8. Egorin, M.J., Sentz, D.L., Zuhowski, E.G., Dobson, J.M., Schulte, T.W., Neckers, L.M., Eiseman, J.L. 1999. PC3 Human Prostate Xenograft Retention Of, & Oncoprotein Modulation by, 17-Allylaminogeldanamycin (17AAG) in Vivo. [Abstract No. 3409]. Proc. Amer. Assoc. Cancer Res., 40, 517.
  9. Hale, J., Bigelow, J., Mathews, L., McCormack, J. 1999. Analytical and Pharmacokinetic Studies with 5-Chloro-2'-deoxycytidine. [Abstract No. 2590]. Proc. Amer. Assoc. Cancer Res., 40, 391.
  10. Kuffel, M.J., Squillace, D.P., Reid, J.M., Ames, M.M. 1999. Cytochrome P450-catalyzed Metabolism of the Aminoflavone Analog NSC 686288 in Human and Rat Liver Microsomes: the Role of CYP1A Subfamily Enzymes. [Abstract No. 2544]. Proc. Amer. Assoc. Cancer Res., 40, 384.
  11. Brown, A.P., Morrissey, R.L., Rodvoid, K.A., Tolhurst, T.A., Donohue, S.J., Tomaszewski, J.E., Levine, B.S. 1999. Intravenous Plasma Elimination Kinetics and Toxicity of an Aminoflavone in the Dog. [Abstract No. 2579]. Proc. Amer. Assoc. Cancer Res., 40, 390.
  12. Chang, C.J.G., Smith, A.C., Elliott, P.J., Pien, C.S., Fulton, R., Thompson, R.B., Page, J.G. 1999. Multiple Dose Toxicity and Proteasome Inhibition of PS-341 (NSC 681239) in Rats. [Abstract No. 3416]. Proc. Amer. Assoc. Cancer Res., 40, 518.
  13. Green, G.E., Ramanathan-Girish, S., Magon, M., Catz, P., Donohue, S.J., Schweikart, K.M., Tomaszewski, J.E., Tyson, C.A. 1999. Toxicity and Comparison of Oral Bioavailability of Dimethyl Amino Benzoylphenylurea (NSC 639829) in Beagle Dogs and Fischer 344 Rats. [Abstract No. 2551]. Proc. Amer. Assoc. Cancer Res., 40, 385.
  14. Mirsalis, J.C., Schindler-Horvat, J.E., Fairchild, D.G., Tomaszewski, J.E., Donohue, S.J., Tyson, C.A. 1999. Preclinical Toxicology Studies of Halichondrin B in Rats and Dogs. [Abstract No. 2550]. Proc. Amer. Assoc. Cancer Res., 40, 385.
  15. Noker, P.E., Thompson, R.B., Smith, A.C., Tomaszewski, J.E., Page J.G. 1999. Toxicity and pharmacokinetics of 17-Allylaminogeldanamycin (17-AAG, NSC 330507) in Dogs. [Abstract No. 804]. Proc. Amer. Assoc. Cancer Res., 40, 121.
  16. Page, J.G., Noker, P.E., Tomaszewski, J.E., Smith, A.C. 1999. Lack of Schedule Dependent Toxicity of 17-Allylaminogeldanamycin (17-AAG, NSC 330507) in Rats. [Abstract No. 805]. Proc. Amer. Assoc. Cancer Res., 40, 121.
  17. Schweikart, K.M., Tosca, P.J., Bollinger, L., Ryan, M., Turner, N., Tomaszewski, J.E. 1999. Toxicity of Pc4± Laser Treatment in Mice and Rabbits. [Abstract No. 2555]. Proc. Amer. Assoc. Cancer Res., 40, 386.
  18. Tomaszewski, J.E., Schweikart, K.M., Covey, J.M., Turner, N., Tosca, P.J., Hassler, C., Simpson, B., Fogler, W.E., Sim, B.K.L. 1999. Pharmacokinetics and Range-finding Toxicity Studies of Recombinant Human Endostatin™ in Cynomolgus Monkeys. [Abstract No. 2553]. Proc. Amer. Assoc. Cancer Res., 40, 385.
  19. Tomaszewski, J.E., Schweikart, K.M., Covey, J.M., Turner, N., Tosca, P.J., Simpson, B., Fogler, W.E., Sim, B.K.L. 1999. Mouse Pharmacokinetics and Pharmacological Basis for Drug Development of Recombinant Human Endostatin™. [Abstract No. 2554]. Proc. Amer. Assoc. Cancer Res., 40, 386.
  20. Tosca, P.J., Bollinger, L., Zutshi, A., Ryan, M., Turner, N., Wang, Q.C., Pai, L., Pastan, I., Schweikart, K.M., Tomaszewski, J.E. 1999. Pharmacokinetics and Toxicity of Pseudomonas Exotoxin Monoclonal Antibody Conjugate LMB-9 in Cynomolgus Monkeys. [Abstract No. 3126]. Proc. Amer. Assoc. Cancer Res., 40, 473.
  21. Turner, N., Tosca, P.J., Bollinger, L., Hassler, C., Ryan, M., Kreitman, R.J., Wang, Q.C., Pastan, I., Schweikart, K.M., Tomaszewski, J.E. 1999. Pharmacokinetics and Toxicity of Pseudomonas Exotoxin Monoclonal Antibody Conjugate BL22 in Cynomolgus Monkeys. [Abstract No. 3127]. Proc. Amer. Assoc. Cancer Res., 40, 473.
  22. Tomaszewski, J.E., 1999. Correlation of Clinical and Preclinical Bone Marrow Toxicity Data for Selected Anticancer Drugs. In Vitro Human Tissue Models in Risk Assessment Society of Toxicology Contemporary Concepts in Toxicology Workshop. Ellicott City, MD.
  23. Tomaszewski, J.E., 1999. Development of Novel Biological Agents: Pseudomonas Immunotoxin Conjugates. Twentieth Annual Meeting of the American College of Toxicology, McLean, VA.
  24. Chan, Kenneth K., Jiang, Chun, Zheng, Helen H., Chiu, Ming H., and Covey, Joseph, 1999. Pharmacokinetics of S(-)XK469 (NSC-698216) in CD1F2 Mice and Fischer 344 Rats. [Abstract No. 546]. AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. Washington, DC. November 1999.
  25. Eiseman, J., Grimm, A., Sentz, D., Lessor, T., Gessner, R., Zuhowski, E., Nemieboka, N., Egorin, M., Hamburger, A., 1999. Pharmacokinetics of 17-Allylamino(17-demethoxy)geldanamycin in SCID Mice Bearing MDA-MD-453 Xenografts and Alterations in the Expression of p185erb-B2 in the Xenografts Following Treatment. [Abstract No. 536]. AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. Washington, DC. November 1999.
  26. Fortier, A.H., Fogler, W.E., Tomaszewski, J.E., DuVall, M., Schweikart, K.M., Covey, J.M., Paciotti, G.F., Ruiz, A., Sim, B.K.L., 1999. Pharmacologic Design and Results of a 28-Day Intravenous Toxicity Study with Recombinant Human Endostatin Protein in Cynomolgus Monkeys. [Abstract No. 417]. AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. Washington, DC. November 1999.

About the Branch Chief

For information regarding the TPB, please contact Dr. Jerry M. Collins, Associate Director, collinsje@mail.nih.gov