Skip to Content
Developmental Therapeutics Program (DTP)
Last Updated: 04/02/15

TPB Publications

2006 Publications

  1. Saavedra, J.E., Srinivasan, A., Buzard, G.S., Davies, K.M., Waterhouse, D., Inami, K., Wilde, T.C., Citro, L.M., Cuellar, M., Deschamps, J.R., Parrish, D. Shami, P.J., Findlay, V.J. Jia, L., Ji, X., Keefer, L.K., 2006. PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity. J. Med. Chem. 49, 1157-1164.
  2. Coward, L.C. Kerstner-Wood, Noker, P., Gorman, G., Pellecchia, M., Reed, J.C., Jia, L. 2006. Quantitative determination of Apogossypol, a pro-apoptotic analog of gossypol, in mouse plasma using LC/MS/MS. J. Pharm. Biomed. Anal. 42: 581-586.
  3. Jia, L., Noker, P.E., Coward, L. Gorman, G. Protopopova, M., Tomaszewski, J.E. 2006. Interspecies pharmacokinetics and in vitro metabolism of SQ109 Br. J. Pharmacol. 147(5):476-85.
  4. Buhrow, S.A., Reid, J.M., Jia, L., Covey, J., Kobs, D.J., Grossi, I. M., Ames, M.M. 2006. LC/MS/MS assay and dog pharmacokinetics of the dimeric pyrrolobenzodiazepine SJG-136 (NSC 694501). J. Chromatogr. 840: 56-62.
  5. Shami, PJ., Saavedra, J. E., Bonifant, C. L., Chu, J.; Udupi, V.; Malaviya, S.; Carr, B. I.; Kar, S.; Wang, M.; Jia, L.; Ji, X.; Keefer, L. K. 2006. Antitumor Activity of JS-K [O2-(2,4-Dinitrophenyl) 1-[(4-Ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and Related O2-Aryl Diazeniumdiolates in Vitro and in Vivo. J. Med. Chem. 49(14): 4356-4366.
  6. Beumer, J. H., E. Joseph, M.J. Egorin, J.M. Covey, & Eiseman, J. L., 2006. Quantitative Determination of Zebularine (NSC 309132), a DNA Methyltransferase Inhibitor, and Three Metabolites in Murine Plasma by High-performance Liquid Chromatography Coupled with On-line Radioactivity Detection. J. Chromatog. B, 831, 147-155.
  7. Li M, Wang H, Hill, D, Stinson S, Veley K, Grossi I, Peggins, JO, Covey, JM and Zhang, R. (2006). Preclinical pharmacology of the novel antitumor agent adaphostin, a tyrphostin analog that inhibits bcr/abl. Cancer Chemother Pharmacol , 57 (5), 607-14.
  8. Wang, Z., H. Wang, J.K. Rhie, J.M. Covey, P. Liang, S. Wang, et al., 2006. Determination of Desoxyepothilone B in Nude Mice Plasma by Liquid-liquid Extraction and Reversed-phase High-performance Liquid Chromatography. J. Pharmaceut. Biomed. Anal., 42, 272-276.
  9. Beumer, J. H., E. Joseph, M.J. Egorin, R.S. Parker, D.Z. D'argenio, J.M. Covey, et al., 2006. A Mass Balance and Disposition Study of the DNA Methyltransferase Inhibitor Zebularine (NSC 309132) and Three of its Metabolites in Mice. Clini. Cancer Res., 12, 5826-5833.
  10. Zhang, Y., Y. Hua, D.M. Benbrook, J.M. Covey, G. Dai, Z. Liu, Z., et al., 2006. High Performance Liquid Chromatographic Analysis and Preclinical Pharmacokinetics of the Heteroarotinoid Antitumor Agent, SHetA2. Cancer Chemother. Pharmacol, 58, 561-569.
  11. Beumer, J. H., J.L. Eiseman, R.A. Parise, E. Joseph, J.L. Holleran, J.M. Covey, et al., 2006. Pharmacokinetics, Metabolism, and Oral Bioavailability of the DNA Methyltransferase Inhibitor 5-Fluoro-2?-deoxycytidine in Mice. Clin. Cancer Res., 12, 7483-7491.

About the Branch Chief

For information regarding the TPB, please contact Dr. Jerry M. Collins, Associate Director, collinsje@mail.nih.gov