C-RAF protein PRO [primary]
Experiment Id: 374548 Pattern Id: MT18285 Clone number: |
Rationale: Aberrations in oncogenes and tumor suppressors frequently affect the activity of critical signal transduction pathways. To analyze systematically the relationship between the activation status of protein networks and other characteristics of cancer cells, reverse phase protein array (RPPA) profiling of the NCI60 cell lines for total protein expression and activation-specific markers of critical signaling pathways was performed. |
Investigator(s): Davies, Dr. Michael The University of Texas - M D Anderson Cancer Center |
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Method: Rev Prot Lysate Array Unit: log2 relative protein level Protocol: Protein lysates were diluted to a uniform protein concentration, denatured, and dilution series printed onto slides. These arrays were probed with antibody specific for the indicated protein, using the DAKO signal amplification system. |
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An experimental system for automatically partitioning GenBank sequences into a non-redundant set of gene-oriented clusters. |
Presents information on official nomenclature, aliases, sequence accession numbers, phenotypes, EC numbers, MIM numbers, UniGene clusters, map information, Gene Ontology annotations, and relevant web sites. Replaces LocusLink. |
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A catalog of human genes and genetic disorders. |
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CGAP provides information on gene expression, SNPs, functional pathways and more in normal, precancerous and cancer cells. |
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Email questions concerning DTP's molecular targets program to: [Moltarget@mail.nih.gov]