Experiment Id: 374556

Pattern Id: MT18293

Clone number:

GenBank Acc:

Rationale: Aberrations in oncogenes and tumor suppressors frequently affect the activity of critical signal transduction pathways. To analyze systematically the relationship between the activation status of protein networks and other characteristics of cancer cells, reverse phase protein array (RPPA) profiling of the NCI60 cell lines for total protein expression and activation-specific markers of critical signaling pathways was performed.

Investigator(s):

Davies, Dr. Michael

The University of Texas - M D Anderson Cancer Center

Method: Rev Prot Lysate Array

Unit: log2 relative protein level

Protocol: Protein lysates were diluted to a uniform protein concentration, denatured, and dilution series printed onto slides. These arrays were probed with antibody specific for the indicated protein, using the DAKO signal amplification system.

Target Data:

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Unigene

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CGAP

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