Skip to Content
Developmental Therapeutics Program (DTP)
Introduction to NCI60 molecular characterization program | Search NCI60 molecular target data | Browse NCI60 molecular target data | Download NCI60 molecular target data

XPA (DNA excision repair, xeroderma pigmentosum A) PRO [primary]

Primary Reference(s):

XPA (DNA excision repair, xeroderma pigmentosum A) PRO

Experiment Id: 719

Pattern Id: MT376

Clone number:

GenBank Acc:

Rationale: XPA is needed for excision repair of DNA damage. Defects in XPA are found in patients with xeroderma pigmentosum group A, a disease characterized by a high incidence of skin cancer.

Investigator(s):

Panasci, Dr. Lawrence

Jewish Central Hospital

Method: Western blot

Unit: Protein levels relative to alpha-Tubulin protein

Protocol: Total cellular extracts were separated by SDS-PAGE, electroblotted onto nitrocellulose membrane, blocked in 5% non-fat milk and hybridized with primary antibody. After washing, the blot was incubated with secondary antibody and visualized with the electrochemiluminescence (ECL) system. Values were standardized with alpha-tubulin and are the mean of 3 experiments.

Target Data:

Compare:

Unigene

An experimental system for automatically partitioning GenBank sequences into a non-redundant set of gene-oriented clusters.

Gene

Presents information on official nomenclature, aliases, sequence accession numbers, phenotypes, EC numbers, MIM numbers, UniGene clusters, map information, Gene Ontology annotations, and relevant web sites. Replaces LocusLink.

OMIM

A catalog of human genes and genetic disorders.

PubMed

Search PubMed for articles on:

CGAP

CGAP provides information on gene expression, SNPs, functional pathways and more in normal, precancerous and cancer cells.

Email questions concerning DTP's molecular targets program to: [Moltarget@mail.nih.gov]

New Target Information Format

s