XPA (DNA excision repair, xeroderma pigmentosum A) PRO [primary]
Experiment Id: 719 Pattern Id: MT376 Clone number: |
Rationale: XPA is needed for excision repair of DNA damage. Defects in XPA are found in patients with xeroderma pigmentosum group A, a disease characterized by a high incidence of skin cancer. |
Investigator(s): Panasci, Dr. Lawrence Jewish Central Hospital |
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Method: Western blot Unit: Protein levels relative to alpha-Tubulin protein Protocol: Total cellular extracts were separated by SDS-PAGE, electroblotted onto nitrocellulose membrane, blocked in 5% non-fat milk and hybridized with primary antibody. After washing, the blot was incubated with secondary antibody and visualized with the electrochemiluminescence (ECL) system. Values were standardized with alpha-tubulin and are the mean of 3 experiments. |
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An experimental system for automatically partitioning GenBank sequences into a non-redundant set of gene-oriented clusters. |
Presents information on official nomenclature, aliases, sequence accession numbers, phenotypes, EC numbers, MIM numbers, UniGene clusters, map information, Gene Ontology annotations, and relevant web sites. Replaces LocusLink. |
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A catalog of human genes and genetic disorders. |
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CGAP provides information on gene expression, SNPs, functional pathways and more in normal, precancerous and cancer cells. |
Email questions concerning DTP's molecular targets program to: [Moltarget@mail.nih.gov]