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Developmental Therapeutics Program (DTP)
Last Updated: 09/12/17

Tumor Repositories:

DCTD/DTP Tumor Repository (catalog for download)
Contact: Christine Pacula-Cox: paculac@mail.nih.gov

DTP has maintained since the early 1960s a low temperature repository of transplantable in vivo-derived tumors and in vitro-established tumor cell lines from various species, located at the National Cancer Institute in Frederick, Maryland. This tumor Repository serves as a resource for viable, contaminant-free experimental tumor lines, many of which are not obtainable elsewhere. The Repository makes these materials available to qualified investigators as a service to the cancer research community.

 

NCI Patient-Derived Models Repository
Contact: Dr. Yvonne A. Evrard: NCI_PDM_Repository@mail.nih.gov

NCI is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs) and in vitro patient-derived cell cultures (PDCs), including mixed cell populations, clonal cell lines, and fibroblast cell lines, to serve as a resource for public-private partnerships and for academic drug discovery efforts. These PDMs will be clinically-annotated with molecular information available in an easily accessible database and will be available to the extramural community.

About the Branch Chief

Dr. Melinda Hollingshead has served as Chief of the Biological Testing Branch at NCI since 2005. The Biological Testing Branch (BTB) establishes patient derived xenograft (PDX) models, isolates cell lines from PDX models and conducts preclinical anti-cancer drug evaluations in relevant rodent models. Additionally, the BTB manages the distribution of cell lines and tumor samples from the DCTD Repository. More…