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Developmental Therapeutics Program (DTP)
Last Updated: 07/23/15

List of Supported INDs/DMFs

Small Molecule Cancer Drugs

Small Molecule Cancer Drugs: NSC Number
Deoxyspergualin (NSC 356894)
Cyclopentenyl Cytosine (CPEC) 3 (NSC 375575)
Carboxyaminoimidazole (CAI) 3 (NSC 609974)
Fostriecin, Sodium (NSC 339638)
TNP-470 (Fumagillin Analog) (NSC 642492)
9-Amino[20S]camptothecin (NSC 603071)
Penclomedine (NSC 338720)
Bizelesin (NSC 615291)
O6-Benzylguanine/BCNU (O6BG) (NSC 637037)
Flavopiridol 3 (NSC 649890)
Rebeccamycin Tartrate (NSC 655649)
Perillyl Alcohol (NSC 641066)
Tributyrin (NSC 661583)
Dolastatin 10 (NSC 376128)
UCN-01 3 (NSC 638850)
Quinocarmycin Analog DX-52-1 (NSC 607097)
KRN5500 (NSC 650426)
Bizelesin (Bone Marrow) (NSC 615291)
Depsipeptide NDA (NSC 630176)
Penclomedine (Oral) (NSC 338720)
Cordycepin/Deoxycoformycin (NSC 63984/218321)
Ecteinascidin 743 (NSC 648766)
COL-3 (NSC 683551)
EF-5 (NSC 684681)
PS-341 NDA (NSC 681239)
G3139 (NSC 683428)
SarCNU (NSC 364432)
17-Allylaminogeldanamycin (NSC 330507)
Pc-4 (Silicone Phthalocyanine) (NSC 676418) DMF
PS-341 (Velcade) NDA (NSC 681239)
G3139 (NSC 683428)
Tempol 3 (NSC 142784)
2-Methoxyestradiol (NSC 659853)
Pyroxamide (NSC 696085) DMF
Benzoylphenylurea (NSC 639829)
MS-275 (NSC 706995)
2-Methoxyestradiol (NSC 659853)
Epothilone D (KOS-862) 10 (NSC 703147)
R-(+)-XK-469 (NSC 698215)
Eisai Compound E7389 (NSC 707389)
Imexon 10 (NSC 714597)
PT-523 10 (NSC 633713)
8-Chloroadenosine 10 (NSC 354258)
Cytochlor/THU (NSC 371331+112907)
Betulinic Acid (Dermal) 10 (NSC 113090)
Tetrathiomolybdate (TTM) 10 (NSC 714598)
Safingol 10 (NSC 714503)
Buthionine Sulfoximine (BSO) 10 (NSC 326231)
17-Dimethylaminogeldanamycin (NSC 707545)
Fenretinide iv Formulation 10 (NSC 374551)
Pyrrolobenzodiazepine dimer (NSC 694501)
5-Iodo-2-pyrimidinone-2'-deoxyribose (IpdR) 10 (NSC 726188)
Fluorodeoxycytidine + THU 10 (NSC 48,006+112907)
Methoxyamine + Temozolomide 10 (NSC 3801+362856)
MAP Regimen (MMPR + 6-AN + PALA) 10 (NSC 40774+21206+224131)
4-HPR Lym-X-Sorb Oral Form 10 (NSC 374551)
4-HPR + Safingol 10 (NSC 374551+714503)
18F-EF5 and EF5 (NSC 734904)
PXD-101 (NSC 726630)
Aminoflavone (NSC 710464)
MLN518 (Tandutinib) (NSC 726292)
CDDO 10 (NSC 711136)
ABT-888 37,44 (NSC 737664)
DB-67 10 (NSC 708298)
Batracylin (NSC 320846)
AT-101 (Gossypol) 10 (NSC 726190)
ABT-888/Topotecan Combination 44 (NSC 737664)
1-Methyltryptophan (NSC 721782)
FAU (NSC 678515)
Dimethane Sulfonate 3 (NSC 281612)
FdC/THU 44 (NSC 48006+112907)
Indenoisoquinolines 44 (NSC743400&725776)
TdCyd (NSC 764276)
Endoxifen (NSC 749798)
LUM015 (NSC D77650)
NIR Flurophore ZW800 (NSC D772596-M)

Biological Cancer Agents

Biological Cancer Agents: NSC Number
LMB-1 [B3-NLysPE38] 3 (NSC 651311)
r-V-CEA(180k) 3 (NSC 649024)
r-V-MAGE1 3 (NSC 658894)
LMB-7 [B3-(Fv)PE38] 3 (NSC 658931)
MART-1 Peptide/ISA 3 (NSC 672643)
PCLUS 3-18MN, 6.1-18MN, P-18MN/ISA [HIV]3 (NSC 658895, 663850)
ras 5-17 Peptides C12, V12, D12 /Detox 3 (NSC 667937/665824/667938)
r-V-CEA(70k) 3 (NSC 649203)
ras Proteins (C12, D12, V12)/QS21 3 (NSC 674779/674780/674781)
r-Ad2-MART-1 3 (NSC 674304)
r-Ad2-gp100 3 (NSC 674305)
LMB-2 [Anti-Tac(Fv)-PE38] 3 (NSC 676422)
r-V-PSA 3 (NSC 659642)
LMB-7 (Intrathecal Protocol) 3 (NSC 658931)
r-V-B7.1 3 (NSC 674306)
erb-38 [e23(dsFv)PE38] 3 (NSC 683039)
LMB-9 [B39dsFv)PE38] 3 (NSC 691236)
BL22 [RFB4(dsFv)PE38] 3 (NSC 691237)
Endostatin (NSC 704805)
Endostatin (NSC 704805)
IL-12 + IL-2 3 (NSCs 672423 & 373364)
Angiostatin (NSC 703940)
r-V-CEA/TRICOM + r-F-CEA/TRICOM 3 (NSCs 710067 & 710068)
r-V-TRICOM + r-F-TRICOM 3 (NSCs 708039 & 710658)
7G7 Monoclonal Antibody 3 (Waldmann)
hsp70 E7 r-DNA Vaccine 10 (NSC 723254)
Chimeric E7/HSP70 DNA Vaccine 10 (NSC 723254/5)
VH4-34 Monocolonal Antibody 10 (NSC 711294)
MR1-1 Immunotoxin (dsvPE38KDEL) 10 (NSC 718877)
EGFRvIII Peptide Vaccine 10 (NSC 710294)
pING-TRYP2 10 (NSC 723254)
MV-NIS (NSC 731414)
CMV Lipopeptide Vaccines 10 (NSCs 721433 & 721434)
Ad5-Delta24-RGD 10 (NSC 723256)
Reolysin (Reovirus SeroType3) (NSC 729968)
Multiple Myeloma Vaccine (U266/H929) 10 (NSC 723253)
IL-6 10 (NSC 720836)
phAFP + phGM-CSF Plasmid + AdVhAFP 10 (NSC 725180/1/2)
Ad5.SSTR/TK.RDG 10

AIDS DRUGS

AIDS DRUGS: NSC Number
Dideoxycytidine (ddC) 3 NDA (NSC 606170)
Dideoxyadenosine (ddA) 3 (NSC 98700)
Dideoxyinosine (ddI) 3 NDA (NSC 612049)
3TC [In Part] NDA (NSC 620753)
A-77003 (Protease Inhibitor) (NSC 640441)
KNI-272 (Protease Inhibitor) 3 (NSC 651714)
F-ddA 3 (NSC 613792)
Isis 5320 (NSC 665353)
(+)-Calanolide A (NSC 650886)

OTHER AGENTS

OTHER AGENTS: NSC Number
FP-TZTP (PET No. 01) 3 N/A
MeFBAWAY (PET No. 02) 3 N/A
FCWAY (PET No. 03) 3 N/A
18F-Paclitaxel (PET No. 04) 3 N/A
FPWAY (PET No. 05) 3 N/A
18Fluorocholine 32 (NSC 720948)
Antalarmin 3 (NIMH)
Ethambutol Analog (SQ109) 35 (NSC 722041)
18F -ACBC 32 (NSC 726817)
64CuATSM 32 (NSC 729307)
18F -Galacto-RGD 32 (NSC 729490)
111Indium-CHX-AÓ DTPA Trastuzumab 44 (NSC 740377)
Sodium 2,2-Dimethylbutyrate (ST20) 42 (NSC 741804)
CDD-0102 42 (NSC 743016)
A0001 42 (NSC 742681)

About the Branch Chief

For information regarding the TPB, please contact Dr. Jerry M. Collins, Associate Director, collinsje@mail.nih.gov