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Developmental Therapeutics Program (DTP)
Last Updated: 07/23/15

List of Supported INDs/DMFs

Small Molecule Cancer Drugs

Small Molecule Cancer Drugs: NSC Number
Deoxyspergualin (NSC 356894)
Cyclopentenyl Cytosine (CPEC) 3 (NSC 375575)
Carboxyaminoimidazole (CAI) 3 (NSC 609974)
Fostriecin, Sodium (NSC 339638)
TNP-470 (Fumagillin Analog) (NSC 642492)
9-Amino[20S]camptothecin (NSC 603071)
Penclomedine (NSC 338720)
Bizelesin (NSC 615291)
O6-Benzylguanine/BCNU (O6BG) (NSC 637037)
Flavopiridol 3 (NSC 649890)
Rebeccamycin Tartrate (NSC 655649)
Perillyl Alcohol (NSC 641066)
Tributyrin (NSC 661583)
Dolastatin 10 (NSC 376128)
UCN-01 3 (NSC 638850)
Quinocarmycin Analog DX-52-1 (NSC 607097)
KRN5500 (NSC 650426)
Bizelesin (Bone Marrow) (NSC 615291)
Depsipeptide NDA (NSC 630176)
Penclomedine (Oral) (NSC 338720)
Cordycepin/Deoxycoformycin (NSC 63984/218321)
Ecteinascidin 743 (NSC 648766)
COL-3 (NSC 683551)
EF-5 (NSC 684681)
PS-341 NDA (NSC 681239)
G3139 (NSC 683428)
SarCNU (NSC 364432)
17-Allylaminogeldanamycin (NSC 330507)
Pc-4 (Silicone Phthalocyanine) (NSC 676418) DMF
PS-341 (Velcade) NDA (NSC 681239)
G3139 (NSC 683428)
Tempol 3 (NSC 142784)
2-Methoxyestradiol (NSC 659853)
Pyroxamide (NSC 696085) DMF
Benzoylphenylurea (NSC 639829)
MS-275 (NSC 706995)
2-Methoxyestradiol (NSC 659853)
Epothilone D (KOS-862) 10 (NSC 703147)
R-(+)-XK-469 (NSC 698215)
Eisai Compound E7389 (NSC 707389)
Imexon 10 (NSC 714597)
PT-523 10 (NSC 633713)
8-Chloroadenosine 10 (NSC 354258)
Cytochlor/THU (NSC 371331+112907)
Betulinic Acid (Dermal) 10 (NSC 113090)
Tetrathiomolybdate (TTM) 10 (NSC 714598)
Safingol 10 (NSC 714503)
Buthionine Sulfoximine (BSO) 10 (NSC 326231)
17-Dimethylaminogeldanamycin (NSC 707545)
Fenretinide iv Formulation 10 (NSC 374551)
Pyrrolobenzodiazepine dimer (NSC 694501)
5-Iodo-2-pyrimidinone-2'-deoxyribose (IpdR) 10 (NSC 726188)
Fluorodeoxycytidine + THU 10 (NSC 48,006+112907)
Methoxyamine + Temozolomide 10 (NSC 3801+362856)
MAP Regimen (MMPR + 6-AN + PALA) 10 (NSC 40774+21206+224131)
4-HPR Lym-X-Sorb Oral Form 10 (NSC 374551)
4-HPR + Safingol 10 (NSC 374551+714503)
18F-EF5 and EF5 (NSC 734904)
PXD-101 (NSC 726630)
Aminoflavone (NSC 710464)
MLN518 (Tandutinib) (NSC 726292)
CDDO 10 (NSC 711136)
ABT-888 37,44 (NSC 737664)
DB-67 10 (NSC 708298)
Batracylin (NSC 320846)
AT-101 (Gossypol) 10 (NSC 726190)
ABT-888/Topotecan Combination 44 (NSC 737664)
1-Methyltryptophan (NSC 721782)
FAU (NSC 678515)
Dimethane Sulfonate 3 (NSC 281612)
FdC/THU 44 (NSC 48006+112907)
Indenoisoquinolines 44 (NSC743400&725776)
TdCyd (NSC 764276)
Endoxifen (NSC 749798)
LUM015 (NSC D77650)
NIR Flurophore ZW800 (NSC D772596-M)

Biological Cancer Agents

Biological Cancer Agents: NSC Number
LMB-1 [B3-NLysPE38] 3 (NSC 651311)
r-V-CEA(180k) 3 (NSC 649024)
r-V-MAGE1 3 (NSC 658894)
LMB-7 [B3-(Fv)PE38] 3 (NSC 658931)
MART-1 Peptide/ISA 3 (NSC 672643)
PCLUS 3-18MN, 6.1-18MN, P-18MN/ISA [HIV]3 (NSC 658895, 663850)
ras 5-17 Peptides C12, V12, D12 /Detox 3 (NSC 667937/665824/667938)
r-V-CEA(70k) 3 (NSC 649203)
ras Proteins (C12, D12, V12)/QS21 3 (NSC 674779/674780/674781)
r-Ad2-MART-1 3 (NSC 674304)
r-Ad2-gp100 3 (NSC 674305)
LMB-2 [Anti-Tac(Fv)-PE38] 3 (NSC 676422)
r-V-PSA 3 (NSC 659642)
LMB-7 (Intrathecal Protocol) 3 (NSC 658931)
r-V-B7.1 3 (NSC 674306)
erb-38 [e23(dsFv)PE38] 3 (NSC 683039)
LMB-9 [B39dsFv)PE38] 3 (NSC 691236)
BL22 [RFB4(dsFv)PE38] 3 (NSC 691237)
Endostatin (NSC 704805)
Endostatin (NSC 704805)
IL-12 + IL-2 3 (NSCs 672423 & 373364)
Angiostatin (NSC 703940)
r-V-CEA/TRICOM + r-F-CEA/TRICOM 3 (NSCs 710067 & 710068)
r-V-TRICOM + r-F-TRICOM 3 (NSCs 708039 & 710658)
7G7 Monoclonal Antibody 3 (Waldmann)
hsp70 E7 r-DNA Vaccine 10 (NSC 723254)
Chimeric E7/HSP70 DNA Vaccine 10 (NSC 723254/5)
VH4-34 Monocolonal Antibody 10 (NSC 711294)
MR1-1 Immunotoxin (dsvPE38KDEL) 10 (NSC 718877)
EGFRvIII Peptide Vaccine 10 (NSC 710294)
pING-TRYP2 10 (NSC 723254)
MV-NIS (NSC 731414)
CMV Lipopeptide Vaccines 10 (NSCs 721433 & 721434)
Ad5-Delta24-RGD 10 (NSC 723256)
Reolysin (Reovirus SeroType3) (NSC 729968)
Multiple Myeloma Vaccine (U266/H929) 10 (NSC 723253)
IL-6 10 (NSC 720836)
phAFP + phGM-CSF Plasmid + AdVhAFP 10 (NSC 725180/1/2)
Ad5.SSTR/TK.RDG 10

AIDS DRUGS

AIDS DRUGS: NSC Number
Dideoxycytidine (ddC) 3 NDA (NSC 606170)
Dideoxyadenosine (ddA) 3 (NSC 98700)
Dideoxyinosine (ddI) 3 NDA (NSC 612049)
3TC [In Part] NDA (NSC 620753)
A-77003 (Protease Inhibitor) (NSC 640441)
KNI-272 (Protease Inhibitor) 3 (NSC 651714)
F-ddA 3 (NSC 613792)
Isis 5320 (NSC 665353)
(+)-Calanolide A (NSC 650886)

OTHER AGENTS

OTHER AGENTS: NSC Number
FP-TZTP (PET No. 01) 3 N/A
MeFBAWAY (PET No. 02) 3 N/A
FCWAY (PET No. 03) 3 N/A
18F-Paclitaxel (PET No. 04) 3 N/A
FPWAY (PET No. 05) 3 N/A
18Fluorocholine 32 (NSC 720948)
Antalarmin 3 (NIMH)
Ethambutol Analog (SQ109) 35 (NSC 722041)
18F -ACBC 32 (NSC 726817)
64CuATSM 32 (NSC 729307)
18F -Galacto-RGD 32 (NSC 729490)
111Indium-CHX-AÓ DTPA Trastuzumab 44 (NSC 740377)
Sodium 2,2-Dimethylbutyrate (ST20) 42 (NSC 741804)
CDD-0102 42 (NSC 743016)
A0001 42 (NSC 742681)

About the Branch Chief

Myrtle Davis, DVM. Ph.D. Myrtle Davis, DVM. Ph.D. is currently the Branch Chief for Toxicology and Pharmacology in the Developmental Therapeutics Program of the Division of Cancer Diagnostics and Treat-ment of the National Cancer Institute and serves as Scientific Director of the Labor-atory of Investigative Toxicology at the Frederick National Laboratory for Cancer Research (FNLCR). More…