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Developmental Therapeutics Program (DTP)
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Last Updated: 06/21/23

FDA-Approved Drugs

1949

Mechlorethamine (NSC 762)
Ethinyl Estradiol (NSC 71423)

1953

TEM (NSC 9706)
Mercaptopurine (NSC 755)
Methotrexate (NSC 740)

1954

Busulfan (NSC 750)

1957

Chlorambucil (NSC 3088) *

1959

Cyclophosphamide (NSC 26271) *
Thiotepa (NSC 6396) *

1961

Vinblastine (NSC 49842) *

1962

Uracil Mustard (NSC 34462)
Fluorouracil (NSC 19893) *

1963

Vincristine (NSC 67574) *

1964

Melphalan (NSC 8806) *
Actinomycin D (NSC 3053) *

1966

Pipobroman (NSC 25154) *
Thioguanine (NSC 752) *

1967

Hydroxyurea (NSC 32065) *

1969

Ara-C (NSC 63878) *
Procarbazine (NSC 77213) *

1970

FUDR (NSC 27640) *
Mithramycin (NSC 24559) *
o-p'-DDD (NSC 38721) *

1973

Bleomycin (NSC 125066) *

1974

Adriamycin (NSC 123127) *
Mitomycin C (NSC 26980) *

1975

Dacarbazine (NSC 45388) *

1976

CCNU (NSC 9037) *

1977

BCNU (NSC 409962) *

1978

cis-Platinum (NSC 119875) *

1979

Daunomycin (NSC 82151) *
Tamoxifen (NSC 180973)

1982

Streptozotocin (NSC 85998) *

1983

Etoposide (NSC 141540) *

1987

Mitoxantrone (NSC 301739) *

1988

Ifosfamide (NSC 109724) *

1989

Carboplatin (NSC 241240) *

1990

Hexamethylmelamine (NSC 13875) *
Idarubicin (NSC 256439)
Levamisole (NSC 177023) *

1991

Fludarabine Phosphate (NSC 312887) *
Pentostatin (NSC 218321) *

1992

Chorodeoxyadenosine (NSC 105014)
Taxol (NSC 125973) *
Teniposide (NSC 122819) *

1994

Navelbine (NSC 608210)

1995

All-t-retinoic acid (NSC 122758) *
Porfimer Na (NSC 603062)

1996

Gemcitabine (NSC 613327)
Gliadel (NSC 714372)
Irinotecan (NSC 616348)
Taxotere (NSC 628503)
Topotecan (NSC 609699) *

1998

Herceptin (NSC 688097)
Ontak (NSC 697979)

2000

Arsenic Trioxide (NSC 706363)
Celebrex (NSC 719627)

2001

Gleevec (NSC 716051)

2003

Velcade NSC 681239) *

2004

Clolar (NSC 606869)
Erbitux (NSC 632307) *

* Drugs marketed for oncology with DTP involvement